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Multiple Sclerosis: Tracking Down The Causes
Over 100,000 people suffer from multiple sclerosis in Germany alone. Despite intensive research, the factors that trigger the disease and influence its progress remain unclear. Scientists from the Max Planck Institute of Neurobiology in Martinsried and an international research team have succeeded in attaining three important new insights into the disease. It would appear that B cells play an unexpected role in the spontaneous development of multiple sclerosis and that particularly aggressive T cells are activated by different proteins. Furthermore, a new animal model is helping the scientists to understand the emergence of the most common form of the disease in Germany. (Nature Medicine, May 31, 2009 & Journal of Experimental Medicine, June 1, 2009)
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GlaxoSmithKline To Cut Some Drug Costs In Emerging Markets
GlaxoSmithKline (GSK) plans to decrease the prices of many of its leading medicines in emerging markets following the success of a pilot program in the Philippines, Andrew Witty, GSK"s chief executive, said, Financial Times reports. Witty said the price cuts are part of an effort to diversify and expand globally.
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Allergan Receives Complete Response Letter For BOTOX(R) (Botulinum Toxin Type A) For Treatment Of Upper Limb Spasticity In Adults
Allergan, Inc. (NYSE:AGN) today announced it has received a complete response letter from the U.S. Food and Drug Administration (FDA) regarding the Company"s Supplemental Biologics License Application (sBLA) for BOTOX® (Botulinum Toxin Type A) to treat upper limb spasticity in post-stroke adults. Allergan submitted its sBLA for this indication in the third quarter of 2008.
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Fresenius Endorses PEAK Campaign Efforts To Reduce Dialysis Patient Mortality

Fresenius Medical Care, which operates the nation"s leading network of dialysis clinics, today endorsed the Performance Excellence and Accountability in Kidney Care (PEAK) campaign recently launched by Kidney Care Partners (KCP) - a coalition of patient advocates, dialysis professionals, care providers and manufacturers working together to improve quality of care for individuals with chronic kidney disease (CKD). The PEAK initiative is designed to significantly reduce the mortality rate for patients in their first year of dialysis. "The PEAK initiative is consistent with our ongoing commitment to improving the quality of care," said Dr. J. Michael Lazarus, Fresenius Medical Care"s chief medical officer. "Fresenius Medical Care has always emphasized quality of care in our facilities, and one area of concern has been the increased risk of death in the first year after starting dialysis treatment. Through our RightStart™ program, we were able to demonstrate that a structured program of prompt medical and educational strategies focused on patients in their first three months on dialysis does improve morbidity and mortality rates. So while we know that high mortality rates are a significant problem, we also know that if the entire kidney care community works together toward a common goal, we can make progress in this critical area." Many factors contribute to first-year mortality among dialysis patients. Individuals starting dialysis face complex challenges, such as control of anemia, dietary changes, and vascular access management. They must also adjust to a demanding regular treatment schedule. During this transition period, patients are most susceptible to complications. PEAK is a quality improvement campaign that seeks to mitigate these challenges, pledging to extend, even save, as many as 10,000 lives and reduce mortality among first-year dialysis patients by 20 percent by the end of 2012. "Improvements in quality of care have been at the top of the kidney care community"s agenda over the past 15 years. Significant progress has been made, but the PEAK initiative raises the bar for the next 10 years," said Lazarus. "It says to patients, their families, and everyone concerned with kidney disease that there is a concrete effort in place to address real problems with actual solutions, using recommendations from leading researchers and experts. At a critical time in their lives, when the risks are greatest, dialysis patients and their families can be confident that the PEAK initiative is contributing to improving the chances for survival and a better life for all dialysis patients." Fresenius Medical Care North America


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