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Nanobiotix Reports Exciting Preclinical Results Using Its NanoXray™ Therapeutics Technology To Destroy Tumors
Nanobiotix, an emerging nanomedicine company, announced exciting preclinical results using its patented nanoXray therapeutics platform to fight tumors. The preclinical study, performed at Institut Gustave Roussy, one of Europe"s leading cancer treatment centers, showed that an intratumoral injection of NBTXR3 nanoparticles and activated via standard radiation therapy led to complete tumor regression in mice at 60 days, compared to zero tumor regression in mice treated with xray only or NBTXR3 only. The study was led by principal investigator, Jean Bourhis, M.D., Ph.D. a prominent radiation oncologist and researcher at Institut Gustave Roussy.
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The Complicated Consumer: Positive Ads Aren't Always The Most Effective
Ads that feature positive emotions, like happiness, are not always the best way to reach consumers, according to a new study in the Journal of Consumer Research.
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SAMe Is Effective In Preventing Formation Of Primary Liver Cancer In Rats
A new study investigated the effectiveness of S-adenosylmethionine (SAMe) in the prevention and treatment of hepatocellular carcinoma (HCC) or primary liver cancer. SAMe, a widely available nutritional supplement, with little known side effects, was found to be effective in preventing the formation of HCC in rats. However, high enough levels of SAMe were not attainable to successfully treat established HCC. The findings are available in the August issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases.
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Growing Retail Clinic Trend Makes Few Inroads In Poor, Underserved Areas

Since 2000, nearly 1,000 "retail clinics" -- offering routine care like sports physicals and immunizations and treatment for minor illnesses like strep throat -- have opened their doors inside pharmacies and grocery stores across the United States. Retail chain operators proposed that the new clinics would improve access to medical care among uninsured or underserved populations. However, these clinics have been opened more often in higher-income areas that are less likely to be classified as medically underserved, according to a new study from the University of Pennsylvania School of Medicine published in the May 25 issue of Archives of Internal Medicine. "There has been a rapid rise in the number of retail clinics across the United States, but this growth is not evenly distributed across communities," says Craig E. Pollack, MD, MHS, an internist and Robert Wood Johnson Clinical Scholar at Penn. "Poorer neighborhoods are less likely to have access to these clinics." By combining mapping software with Census data and a listing of nearly 1,000 retail clinics across the nation, Pollack and his co-author, Katrina Armstrong, MD, MSCE, an associate professor of Medicine and Epidemiology and chief of the division of General Internal Medicine, found that census tracts with retail clinics had a lower population of black residents, lower poverty rates, and higher median incomes than census tracts without retail clinics. Housed in stores including Wal-Mart, Target and chain pharmacies like CVS and Kerr Drugs, retail clinics offer walk-in appointments, often on weekends and evenings, and the visits generally cost less than paying out of pocket for similar services at a doctor"s office or emergency department. But the Penn authors say these "convenience" factors may not help disadvantaged populations if clinics are located too far away to be reached easily. "We know that people living in poorer areas are less likely to have health insurance, less likely to have a regular of medical care, and may have transportation problems that keep them from getting to the doctor," Pollack says. "By tending to locate in richer neighborhoods, retail clinics may not be meeting their full potential to help address these problems." Previous research shows that a third of retail clinic patients pay for their visits out of pocket, and more than 60 percent of patients report not having a primary care provider. Some opt to pay for after-hours, no-wait care because it"s more convenient, even if they have insurance. The new findings suggest that instead of filling an unmet medical need, placement of clinics in more advantaged neighborhoods may act as an adjunct to existing, more traditional medical care perhaps by staying open later than nearby doctors" offices. The authors say that to further expand their reach, municipalities should consider offering incentives to store operators to open clinics in underserved areas where they already operate retail outlets. Currently, nearly a third of all chain stores are located in medically underserved areas. "There may be a real opportunity to put up clinics in underserved areas where there"s already supermarkets and drug stores" Armstrong says. PENN Medicine is a $3.6 billion enterprise dedicated to the related missions of medical education, biomedical research, and excellence in patient care. PENN Medicine consists of the University of Pennsylvania School of Medicine (founded in 1765 as the nation"s first medical school) and the University of Pennsylvania Health System. Penn"s School of Medicine is currently ranked #3 in the nation in U.S.News & World Report"s survey of top research-oriented medical schools; and, according to the National Institutes of Health, received over $366 million in NIH grants (excluding contracts) in the 2008 fiscal year. Supporting 1,700 fulltime faculty and 700 students, the School of Medicine is recognized worldwide for its superior education and training of the next generation of physician-scientists and leaders of academic medicine. The University of Pennsylvania Health System (UPHS) includes its flagship hospital, the Hospital of the University of Pennsylvania, rated one of the nation"s top ten "Honor Roll" hospitals by U.S.News & World Report; Pennsylvania Hospital, the nation"s first hospital; and Penn Presbyterian Medical Center, named one of the nation"s "100 Top Hospitals" for cardiovascular care by Thomson Reuters. In addition UPHS includes a primary-care provider network; a faculty practice plan; home care, hospice, and nursing home; three multispecialty satellite facilities; as well as the Penn Medicine at Rittenhouse campus, which offers comprehensive inpatient rehabilitation facilities and outpatient services in multiple specialties. University of Pennsylvania School of Medicine


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