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Cerebral Palsy Improves After Bone Marrow Stem Cell Procedure
Dr. David Steenblock of Mission Viejo, California, a pioneer in clinical applications of stem cells, is pleased to report the results of a 16 year old girl who suffered from cerebral palsy. The patient had right side paralysis and spasticity since birth. The procedure consisted of removing 300 milliliters of bone marrow from her hip and giving it back to her intravenously. Five hours after the raw bone marrow infusion, E.H. was able to move her right toe for the first time in her life. That evening, she was able to walk, stepping heel to toe on her right foot. By the next day, she was able to straighten out and use her right arm and wrist for the first time. Within three weeks, she was also able to move her fingers on her right hand and hold a cup for the first time.
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CCA, AIMp And NPA Statement: Decriminalisation Of Dispensing Errors
The decriminalisation of dispensing errors is an issue that has united the profession.
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Study Examines Association Of Movie Smoking Exposure And Team Sport Participation With Youths Becoming Established Smokers
Participating in team sports is associated with a reduced likelihood of youths becoming established smokers, according to a report in the July issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. However, exposure to movie smoking appears to be associated with an increased risk of established smoking in both team sport participants and nonparticipants.
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Instrumental Variable Analysis: Is The Cure Worse Than The Disease?

Causal inference is challenging in all non-experimental studies because of the possibility of hidden bias. Hidden bias may exist as a result of failure to control for unobservable factors, such as doctors" practice/prescription patterns. The use of instrumental variable (IV) technique in outcomes research has increased in recent years because even in the presence of hidden bias, such methods may consistently estimate the average causal effects."However, like many techniques borrowed from one discipline and applied to another, there is a tendency to apply this method blindly." claimed Onur Baser, PhD, President with Stationed Research and Assistant Professor of Surgery with University of Michigan, and a sole author of the study. In this paper, I provide an overview of the instrumental variable approach, examine possible tests to check the prerequisite conditions, and illustrate how weak instruments may produce inconsistent and inefficient results. The immediate question that arises is if the IV method is superior to risk adjustment methods such as propensity score matching or multivariate regression in the sense that these methods both cover observable and unobservable factors, why not always use the IV method? Says Dr. Baser, "If the correlation between the instrument and treatment is weak, this may lead to large inconsistencies in IV estimates with the bias in the same direction as that of OLS estimates. Since IV estimates also have larger standard errors than those of OLS estimates, "ò€¦ the cure can be worse than the disease". This will be discussed in Value in Health, the official journal of the International Society for Pharmacoeconomics and outcomes Research. Value in Health (ISSN 1098-3015) publishes papers, concepts, and ideas that advance the field of pharmacoeconomics and outcomes research and help health care leaders to make decisions that are solidly evidence-based. The journal is published bi-monthly and has a regular readership of over 4,000 clinicians, decision-makers, and researchers worldwide. ISPOR is a nonprofit, international organization that strives to translate pharmacoeconomics and outcomes research into practice to ensure that society allocates scarce health care res wisely, fairly, and efficiently. ISPOR


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