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Aegerion Pharmaceuticals Announces Final Lomitapide (AEGR-733) Phase II Data
Aegerion Pharmaceuticals, Inc., a biopharmaceutical company focused on the treatment of cardiovascular and metabolic disease, announced final data from three separate Phase II trials involving its lead cholesterol management compound, lomitapide (AEGR-733), which is a microsomal triglyceride transfer protein inhibitor (MTP-I) small molecule drug. The final data was recently presented at the American Diabetes Association"s "69th Scientific Sessions" in New Orleans, LA on June 7, 2009 and the International Symposium on Atherosclerosis (ISA) in Boston, MA on June 15, 2009.
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Editorial Calls Supreme Court's Pregnancy Leave Decision 'Not Just'
"The Supreme Court keeps finding ways to deny women equal pay and benefits," a New York Times editorial states in response to the court"s 7-2 ruling on Monday that employers are not required to award women credit toward pension benefits for pregnancy leave taken before Congress passed the 1978 Pregnancy Discrimination Act. According to the Times, the ruling reflects reasoning similar to the court"s 2007 decision in which it denied former Goodyear employee Lilly Ledbetter"s "claim for equal pay because it thought she waited too long to file it." In Monday"s decision, the majority "reasoned mainly that the pregnancy leaves predated the 1978 law, and since the law was not retroactive, the discrepancy in benefits was the product of "past completed events that were entirely lawful at the time they occurred,"" the editorial states. It notes that the majority included "two generally reliable votes for equality, Justices John Paul Stevens and David Souter." The editorial continues, "This may sound logical, but it is not just." The editorial says that Justice Ruth Bader Ginsburg, in writing the dissent, "quite correctly" recognized a company"s "ongoing denial of equal benefits not as past discriminatory behavior that started and ended decades ago, but as a current violation of the act." In a similar way, "Goodyear discriminated against Lilly Ledbetter by maintaining her unequal pay for years, not merely the first time the company underpaid her." The Times calls on Congress to "write corrective legislation" on pregnancy leave (New York Times, 5/21).
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Revision Of Lung Cancer Staging System
For the first time in more than 10 years, the universally accepted lung cancer staging system has been revised to more accurately reflect the prognosis for patients with non-small cell lung cancer (NSCLC).
Cardiovascular

International Groups Express Concern About Cambodian 'AIDS Colony'

In an open letter to Cambodia"s prime minister and health minister, more than 100 international HIV/AIDS advocates and human rights organizations "accused the Cambodian government of herding HIV-affected families into an "AIDS colony" outside the capital, Phnom Penh," the Guardian reports (McCurry, 7/28). According to CNN, the letter said the "de facto AIDS colony at Tuol Sambo ... is far away from the jobs, medical facilities and support services" residents had when they lived in the city. The human rights advocates said the HIV-positive residents were moved despite repeated appeals to the government, including from the U.N. (7/28). The groups said they are very concerned about the "life-threatening" conditions in the settlement where 40 families live in "sheet-metal sheds without running water or proper sanitation," writes the Guardian. According to the newspaper, the Cambodian government has spent the past two months moving HIV-positive people from the Borei Keila district of Phnom Penh to Tuol Sambo, "a flood-prone area 15 miles away" (7/28). In June, 20 families with HIV-positive members were evicted from their homes and moved to make way for a Ministry of Tourism garden, according to the Kaiser Daily Global Health Policy Report (6/19). Local officials acknowledged concerns about the settlement and said they were attempting to improve conditions, reports the Guardian. "We are trying to find clean water for them," said Mann Chhoeun, Phnom Penh"s deputy governor. Chhoeun added that there are plans to distribute free medicine via the Centre of Hope mission (7/28). The open letter "acknowledged the international recognition the Cambodian government has received for treating and supporting people living with HIV," CNN reports (7/28). This information was reprinted from globalhealth.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Global Health Policy Report, search the archives and sign up for email delivery at globalhealth.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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