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Studies Examine Morning Sickness Drug, Progesterone Use To Prevent Premature Birth
The following summarizes news coverage on two pregnancy-related studies. ~ Morning sickness: The commonly prescribed heartburn drug metoclopramide -- sold generically and under the brand-names Reglan, Octamide and Maxolon -- can be used to treat morning sickness without harming the health of the fetus, according to a study published on Thursday in the New England Journal of Medicine, Time reports. The drug, which also has anti-nausea properties, is not FDA-approved for use in pregnant women in the U.S., though it is commonly prescribed in European and other countries to treat morning sickness (Park, Time, 6/10). According to the Los Angeles Times, U.S. physicians occasionally prescribe metoclopramide to treat severe morning sickness cases. The new study found that there were no statistically significant differences between infants born to women who took metoclopramide and those who did not. Researchers said that the findings "provide reassurance regarding the safety of metoclopramide for the fetus when the drug is given to women to relieve nausea and vomiting during pregnancy." The study involved 81,703 births among women enrolled in Israel"s largest health HMO, including 33,458 who used the drug (Maugh, Los Angeles Times, 6/11). Jennifer Niebyl, a professor of obstetrics and gynecology at the University of Iowa, said, "There are very few drugs approved for use in the first trimester of pregnancy. But this study could lead to metoclopramide getting approved to treat morning sickness because this is good data with big numbers" (Time, 6/10).~ Progesterone: The hormone progesterone was not effective at preventing premature births among women pregnant with twins, despite evidence suggesting its effectiveness at preventing premature births in single pregnancies, according to a University of Edinburgh study published in the journal Lancet, Reuters reports. Multiple pregnancies have a larger health risk for women and significantly increase the likelihood of miscarriage, premature birth and long-term health problems. The study involved 500 women who took either progesterone or a placebo daily for 10 weeks. Although previous studies have shown that progesterone might prevent premature birth in certain high-risk pregnancies, the new findings show the treatment did not reduce the likelihood of premature delivery or a fetus dying in utero in twin pregnancies. Twenty-five percent of women delivered or had a fetus die before 34 weeks in the progesterone group, compared with 20% in the placebo group (Kahn, Reuters, 6/10).
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Cincinnati, Northern Kentucky Religious Groups Join Efforts To Encourage HIV Testing
A Christian-theater troupe and other area religious leaders are participating in HIV testing efforts targeting the black community in Greater Cincinnati and Northern Kentucky as part of National HIV Testing Day, the Cincinnati Enquirer reports. According to the Enquirer, local public health officials have long struggled to encourage blacks and other groups to get tested for HIV. Increased awareness efforts by black religious leaders and national initiatives - such as the "Test One Million" campaign organized by the Black AIDS Institute in Los Angeles - have recently focused attention on HIV/AIDS in the black community, Mamie Harris, founder and executive director of IV-Charis, the lead agency in Cincinnati for the "Test One Million" campaign, said (O"Farrell, Cincinnati Enquirer, 6/23).
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Personal Exposure Monitors Show Pharmacy Workers Inhale Drugs When Using Air Pressure-Activated Dispensing Machines
AlburtyLab released a report on its comprehensive evaluation of health risks for workers in pharmacies using air pressure-activated drug dispensing machines. The study tested pharmacy workers wearing personal exposure monitors (PEMs) while using the two leading types of air pressure-activated dispensing technologies - the McKesson/Parata Max and the McKesson/Parata RDS. This is the third major study conducted by AlburtyLab examining the issues relating to pharmacy worker exposure.
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Massachusetts' Individual Mandates, Insurance Exchanges Are Examples For National Plan

"Three years into its experiment with near-universal health care, Massachusetts has some "dos and don"ts" for the nation as it grapples with the best way to cover tens of millions of uninsured Americans," the Associated Press reports. "Do require that virtually everyone have health insurance, the overriding goal in Massachusetts. Don"t ignore rising costs, the single greatest threat to the law"s long-term affordability." Massachusetts" 2006 health overhaul has increased the percentage of residents with insurance from 94 to 97 percent by requiring individuals to buy insurance and expanding subsidies to for the poor, but: "costs to the state have been climbing, thousands have paid tax penalties for being uninsured, and some of the newly insured are struggling to find doctors." When the overhaul was enacted, "the budget for Commonwealth Care, the subsidized insurance, soared from $472 million to $628 million as the uninsured flooded into the program faster then anticipated." Now, the state government is overextended. Critics say not addressing costs from the beginning was a mistake that the nation should avoid. To make up for lost time, "Massachusetts is now weighing a change in the system it uses to pay doctors, so they would be rewarded for keeping patients healthy, not performing more tests" (LeBlanc, 7/24). PBS" the NewsHour: "Massachusetts has proved a testing ground for a concept that could emerge as a centerpiece to national health care reform: a health insurance exchange." Insurance plans are subject to minimum standards and the state runs an insurance exchange called "the Connector." "[T]he Connector is, at its most basic, simply a marketplace where people can buy health insurance. But that marketplace can be organized in many different ways, can be given different amounts of authority, and can be open to all consumers or only to select groups. Right now, Congress is debating the shape of a possible national health insurance exchange -- with bills in the House and Senate proposing somewhat different possibilities. Proponents of a strong health insurance exchange say that structured properly, an exchange could help stimulate competition among insurers, cut costs and increase enrollment in insurance plans" (Winerman, 7/23). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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