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Analysis Of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen In Once-Daily Dosing
A sub-analysis of a Phase IIb multinational study(1) with edoxaban(2) - an investigational oral Factor Xa inhibitor - provides insights into why patients with non-valvular atrial fibrillation (AF) receiving edoxaban once daily (QD) experienced fewer bleeding events than patients given edoxaban twice a day (BID). The analysis finds that bleeding associated with edoxaban is most closely correlated with minimum concentration levels of the drug in the blood, and that these trough levels may best predict bleeding events, rather than total exposure or maximum concentration levels.
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Physicians Can Lead Health Care Reform Through Payment And Delivery System Reforms
Physicians can and should play a leading role in achieving health care reform by working towards comprehensive reform of the way health care is paid for and delivered, helping achieve a guaranteed 1.5 percent annual savings in health care costs that would pay for covering all Americans, according to a New England Journal of Medicine Perspective piece published online.
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CMA Calls For Cutting Waste From Medi-Cal, Using Savings To Fund Health Care For Children
The California Medical Association praised state lawmakers for ordering an audit of Medi-Cal"s costly Treatment Authorization Request (TAR) process today and said the state should streamline the program and use the savings to pay for health care for children.
Health Insurance

Moist Wound Healing Reduces Scarring And Promotes Faster Healing

New consensus has been reached by a panel of leading European experts on the guidelines for the treatment of acute minor wounds which states that healing is accelerated by a moist wound environment. To address the issue that the majority of existing wound care guidelines discuss the pathology and treatment of chronic wounds, Novartis Consumer Healthcare, the makers of Savlon, the number one antiseptic first aid brand in the UK, convened a panel of leading European experts to review and comment on the guidelines for the treatment of minor wounds. The panel of medical experts included representatives from the UK, Germany, Poland, Italy and Portugal. "Most of the research and clinical trials available concerned with wound care focus solely on chronic wounds, primarily because the majority of acute minor wounds are not normally treated by healthcare professionals, but at home or at the place where the wound happened," says the dermatology category marketing manager at Novartis Consumer Health in Europe. "We wanted to bring together a panel of experts from different backgrounds related to wound care management to arrive at a consensus of opinion with regard to minor wounds and their treatment." One of the most interesting outcomes from this initiative was that there is widespread consensus regarding the healing benefits of moist wound environments. The new guidelines highlight that rapid healing of the wound is best achieved by providing a moist environment, which accelerates the rate of wound repair by up to forty per cent, compared to leaving the wound to dry out and allowing a dry scab to form. In addition, as a result of moist healing, there is a reduction in the risk of scarring. While the data showing the benefits of moist wound environments on healing time were first published in the 1960s there is still the continued belief that a dry scab is the best dressing for a wound, particularly among consumers. Novartis" European dermatology category marketing manager says: "Our goal, by bringing this group of eminent experts together, was to produce a consensus on the optimal guidelines for minor wound care. Helping us to educate healthcare professionals, and ultimately consumers, on the best way to treat acute minor wounds." The consensus paper2 states that a hydroactive colloid gel, able to both provide and absorb moisture according to the wound"s properties, can generally be recommended for both dry and exuding minor wounds. "This conclusion is particularly exciting for us," says Savlon"s UK brand manager. "We launched Savlon"s award winning3 Advanced Healing Gel into the pharmacy channel last year and have invested time in training pharmacy staff about the advantages of moist healing. It is great to have the added weight of this consensus of opinion and new guidelines to help challenge the common myth that "scabs are good" which we often encounter." The new guidelines will be published in MIMS Dermatology magazine and the Novartis Consumer Health award-winning Knowledge Bank re is being updated to incorporate the panel"s advice and strengthen Savlon"s four-step ethos: cleanse, treat, heal and protect, heroing Advanced Healing Gel. For more information on the Savlon range please visit http://www.savlon.co.uk Savlon


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