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UBC Researchers Develop New Method To Study Gambling Addictions
UBC researchers have created the world"s first animal laboratory experiment to successfully model human gambling. The advance will help scientists develop and test new treatments for gambling addictions, a devastating condition that affects millions worldwide.
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Individuals Who Apply Pesticides Are Found To Have Double The Risk Of Blood Disorder
A study involving 678 individuals who apply pesticides, culled from a U.S. Agricultural Health Study of over 50,000 farmers, recently found that exposure to certain pesticides doubles one"s risk of developing an abnormal blood condition called MGUS (monoclonal gammopathy of undetermined significance) compared with individuals in the general population. The disorder, characterized by an abnormal level of a plasma protein, requires lifelong monitoring as it is a pre-cancerous condition that can lead to multiple myeloma, a painful cancer of the plasma cells in the bone marrow. The study will appear in the June 18 issue of Blood, the official journal of the American Society of Hematology.
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'Green' Fireworks May Brighten Eco-Friendly 4th Of July Displays In Future
With millions of people in the United States eagerly awaiting those July 4 fireworks displays - and our Canadian neighbors doing likewise for their July 1 Canada Day celebrations - here"s a prospect for those light shows of the future likely to ignite a smile on Mother Nature"s face: A new generation of "green" fireworks is quietly making its way toward the sky.
Oncology

New Anesthesia Technique Lets Patients Cooperate During Carotid Surgery

Can a patient be awake and communicating with the anesthesiologist and surgeon during general anesthesia? With a new "cooperative patient" anesthesia technique, the answer is yes, according to a study in the June issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS). An Italian research team, led by Dr. Sergio Bevilacqua of Ospedaliera Universitaria Careggi, Florence, report on the use of their "cooperative patient general anesthesia" technique in 181 patients undergoing carotid artery surgery (endarterectomy) for stroke prevention. The patients received conventional general anesthesia up to the time that the carotid artery was clamped, as must be done so that the surgeon can repair it. At that time, the general anesthetic was reduced, and the patients received an infusion of remifentanil a morphine-like drug that suppresses pain but permits the patient to regain consciousness. During this part of the procedure, the patients were able to respond to simple commands, such as to open their eyes or squeeze a toy in their hand. This permitted the surgeon to verify that the blood supply to the brain remained adequate during surgery. Communication Allows Monitoring of Brain Blood Supply During Surgery The cooperative technique was successfully carried out in all but two patients, who were kept on general anesthesia. All of the remaining patients were able to respond to the surgeon"s commands. In about twelve percent of cases, the responses from the conscious patient led the surgeon to take additional steps to protect the brain blood flow. Most patients reported no problems with related to being conscious during their surgery. Ninety-nine percent of patients found the experience nonstressful sometimes even pleasant. Most described the experience as dreamlike; although some had more vivid recollections, none reported any pain or distress. Both patients and surgeons were happy with the anesthesia technique. Carotid endarterectomy is a common procedure to prevent stroke in patients with atherosclerosis ("hardening") of the carotid arteries supplying blood to the brain. Local anesthesia can be used, leaving the patient conscious for monitoring during the procedure. This allows the surgical team to monitor the patient"s condition during surgery. However, many patients and surgeons are uncomfortable with this technique. The new study finds cooperative patient general anesthesia to be a "safe and satisfactory" technique for use in carotid surgery. By allowing the patient to respond to simple commands, it provides the surgeon with valuable information to guide the procedure. The procedure appears safe, pain free, and not disturbing or traumatic for the patient, the researchers write. About the IARS The International Anesthesia Research Society is a nonpolitical, not-for-profit medical society founded in 1922 to encourage, stimulate, and fund ongoing anesthesia-related research and projects that will enhance and advance the anesthesiology specialty. The IARS has a worldwide membership of 15,000 physicians, physician residents, and others with doctoral degrees, as well as health professionals in anesthesia-related practice. In additional to publishing the monthly scientific journal Anesthesia & Analgesia, the IARS sponsors an annual clinical and scientific meeting, funds anesthesia-related research, and sponsors the Global Perioperative Research Organization (GPRO). IARS


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