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Lexicon Initiates Phase 2 Clinical Trial Of LX1032 In Patients With Carcinoid Syndrome
Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease, announced today that it has initiated a Phase 2 clinical trial of LX1032, the company"s oral drug candidate for managing gastrointestinal symptoms associated with carcinoid syndrome. LX1032 is designed to reduce serotonin production in patients with metastatic carcinoid tumors. Elevated levels of serotonin contribute to the gastrointestinal and possibly other symptoms experienced by these patients.
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Key To Potential New Treatment For Allergy-Induced Asthma Identified By Yale Team
In research that could lead to new asthma drugs, scientists at Yale School of Medicine, Hydra Biosciences of Cambridge, Massachusetts, and the University of California, San Francisco have discovered that a protein may be a trigger of allergy-induced asthma in mice. They also demonstrated how a drug known to reduce inflammatory and neuropathic pain may also inhibit asthma symptoms in mice. Their paper is published in the May 18-22 online Early Edition of the Proceedings of the National Academy of Sciences.
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Self-Regulation In Alcohol Advertising Not Working, As Ads Target Younger Drinkers
Addiction scientists are calling for tighter regulation of alcohol advertising, as new research shows that self-regulation by the alcohol industry does not protect impressionable children and youth from exposure.
Mental Health

Older Eyewitnesses May Be Unreliable

Older eyewitnesses can inadvertently add or change aspects of their account if they have the chance to speak to another eyewitness. This is one of the findings of Jane Montague and colleagues from University of Derby who will present their research at the British Psychological Society"s Division of Forensic Psychology"s Annual Conference today, Wednesday 24th June. The conference is being held the University of Central Lancashire, Preston. A group of 32 older participants were split in to two groups. The participants in the first group witnessed a DVD recording of a crime and recounted what they remembered - just after witnessing it and again one week later. The second group was made up of "pairs" (either married couples or friends) who were interviewed using the same time scale but who had the opportunity to discuss what they had seen during the intervening week. Preliminary results showed that some details were forgotten or slightly changed across the whole group whilst some similar added details (such as colours of clothing) appeared in the accounts from collaborators. Jane said: "It is too early to draw firm conclusions but this does seem to indicate that having the opportunity to discuss what was seen with another witness does have an effect on what is reported afterwards. This could have major implications for the police trying to interview witnesses sometime after the event." "Further research will establish whether it is this or the natural process of forgetting over time that is the more significant in influencing elderly witnesses" accounts of criminal incidents." The conference is being held at the University of Central Lancashire from the 23rd to 25th July. British Psychological Society


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