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A Real-Life Example Of Humans' Dual Vision System
It"s rare when real-world events perfectly mirror experiments that scientists are conducting.
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New York Times Examines Pilot Program To Fight Drug-Resistant TB In South African Communities
The New York Times examines a Doctors Without Borders pilot program to fight drug-resistant tuberculosis in South Africa that allows patients to stay in their homes rather than be isolated in hospital during treatment. The program, which is supported by the city of Cape Town and the Western Cape Province, aims to "show that such patients can be successfully treated in an impoverished community ň€¦ even while they are still infectious," the New York Times writes.
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CPhA Applauds Efforts To Help Seniors Afford Prescription Medications
Congressional leaders and leading pharmaceutical companies have come up with a plan to reduce medication costs for millions of senior citizens enrolled in the Medicare Part D Prescription Drug program. In combination with other discount programs and rebates, the savings to the U.S. government could represent $80 billion. The Pharmaceutical Research and Manufacturers of America (PhRMA) is leading the charge to specifically close the coverage gap for patients whose medications costs fall into the "doughnut hole."
Medical Devices

Rat Model Of Hepatic Encephalopathy And Prehepatic Portal Hypertension

A research article published in the World Journal of Gastroenterology refers. The research team lead by Dr. Gabriela Beatriz Acosta, observed that the activity of GS was increased in the hippocampus in PH rats. There was a significant decrease in glutamate uptake in both brain areas, which was more marked in the hippocampus. The decrease in glutamate uptake might be caused by deficient transport function and persistent glutamate activity, which is not metabolized. This leads to severe damage in the cells of the central nervous system (CNS), associated with the presence of moderate ammonia concentration in the blood, as observed in this model. These results demonstrated that partial stricture of the portal vein is able to modify normal function in important areas of the rat brain. These results suggest that, in PH this pathology, there are differences between both regions of the brain, possibly caused by the toxic metabolic action of ammonia and glutamate, and perhaps glutamine, in the brain, among other factors. Using this model, it may be possible to understand more clearly the mechanism of toxicity and defense of the brain against the two toxic substances: ammonia and the excitatory neurotransmitter glutamate. The study is important for understanding of some of the mechanisms related to HE. Reference: Acosta GB, Fernández MA, RosellĂö DM, Tomaro ML, Balestrasse K, Lemberg A. Glutamine synthetase activity and glutamate uptake in hippocampus and frontal cortex in portal hypertensive rats. World J Gastroenterol 2009; 15(23): 2893-2899 http://www.wjgnet.com/1007-9327/15/2893.asp Correspondence to: Dr. Gabriela Beatriz Acosta, Institute of Pharmacological Research (ININFA), National Research Council of Argentina (CONICET) and University of Buenos Aires, JunĂ­n 956. 5th floor, C1113AAD, Buenos Aires, Argentina. Lin Tian World Journal of Gastroenterology


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