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Office Of The National Alzheimer's Project Act Will Produce A National Strategic Plan For Alzheimer's Research, Care, And Related Supportive Services
U.S. Senators Mel Martinez (R-FL) and Evan Bayh (D-IN) introduced a measure to create a collaborated system for researching, treating and eliminating Alzheimer"s disease. The proposal will create an Office of the National Alzheimer"s Project within the White House, and will coordinate all research, clinical care and service toward the prevention, care, and cure of Alzheimer"s. This office will produce a national strategic plan to help assure that the millions of Americans who now have Alzheimer"s and the millions of potentially at-risk Americans will have a coordinated effort to target the 6th leading cause of death in the United States.
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Rat Model Of Hepatic Encephalopathy And Prehepatic Portal Hypertension
A research article published in the World Journal of Gastroenterology refers. The research team lead by Dr. Gabriela Beatriz Acosta, observed that the activity of GS was increased in the hippocampus in PH rats. There was a significant decrease in glutamate uptake in both brain areas, which was more marked in the hippocampus. The decrease in glutamate uptake might be caused by deficient transport function and persistent glutamate activity, which is not metabolized. This leads to severe damage in the cells of the central nervous system (CNS), associated with the presence of moderate ammonia concentration in the blood, as observed in this model. These results demonstrated that partial stricture of the portal vein is able to modify normal function in important areas of the rat brain.
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Study Offers New Insights Into Morphine-Induced Tolerance And Increased Pain Sensitivity
A study published in the June issue of Anesthesiology has shown that a drug metabolite of the opioid morphine may be a key factor in the paradoxical increased sensitivity to pain caused by chronic morphine use. For the first time, this metabolite (called morphine-6 glucuronide, or M6G) was shown to act independently of the pain receptors typically targeted during morphine administration.
Diagnostics

Six Finance Senators Strive For Bipartisan Compromise

As the public face of health reform devolves into a partisan fight - with one GOP Senator [Jim DeMint, S.C.] saying the reform push is President Obama"s "Waterloo," and Democrats retorting that Republicans would derail the overhaul for political gain - a group of legislators in the Senate Finance Committee has continued to strive for a compromise behind closed doors, the Christian Science Monitor reports. "If a bipartisan compromise is to clear Congress this year, its main lines are likely to emerge here." The group includes Sens. Max Baucus, D-Mont., Charles Grassley, R-Iowa, Orrin Hatch, R-Utah, Michael Enzi, R-Wyo., Kent Conrad, D-N.D., and Olympia Snowe, R-Maine. "We"re really trying to grapple with reform of the entire system, if at all possible," Snowe said (Chaddock, 7/21). These and other "members of the Senate Finance Committee have seemingly ignored the hubbub, and a presidential deadline, as they huddle daily in pursuit of a breakthrough bill," the Washington Post reports. Senior members, including Grassley, the top Republican, remained hopeful that the panel would reach its accord before the Senate breaks on Aug. 7. Such a measure would achieve the administration"s goals for expanding coverage and lowering costs "without relying on a surtax on wealthy households," while withstanding the scrutiny of wary budget officials and enjoy some Republican support. Senators floated another possible idea to pay for the overhaul Tuesday, the Post reports, "to tax insurers for very generous health policies. The idea is a variation on a provision that Baucus, Grassley and others on the committee had pushed: to tax beneficiaries who receive generous policies through their employers" (Murray and Connolly, 7/22). The GOP members of the negotiating group appeared unfazed by the political turmoil elsewhere in Congress and at the White House, Roll Call reports. Even as Grassley criticized the latest attacks against Republicans - and, he noted, some conservative Democrats - by the administration, he said the Finance negotiators remained fully committed. Snowe said, "I think (the partisan sniping is) to be expected, frankly, on both sides. But the key for us is to stay focused here on what we need to do" (Drucker, 7/22). In a separate story, Roll Call reports that Senate Majority Leader Harry Reid, D-Nev., was "hopeful" that Finance would reach its compromise this week, and said the president"s sometimes-combative steps to influence the debate were helpful. "We must keep our eye on the prize," Reid said. "The prize is health care reform" (Pierce, 7/21). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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