Categories
Cardiovascular
Diagnostics
Endocrinology
Health Insurance
Medical Devices
Mental Health
Nutrition
Oncology
Public Health
Sexual Health
Popular Articles
Burdock Root

Nottingham University Selects Simplexo Enterprise For Five Year Clinical Trial, UK
Simplexo Enterprise, an enterprise search tool, has been selected by Nottingham University to enable the retrieval of information across a five-year clinical trial by its Division of Stroke Medicine into the causes and effects of strokes. The trial team is gathering and analysing information from more than 500 patients and several governing bodies in over 20 countries, including the UK, the United States, China, India and Australia.
generic viagra online
System Accurately Predicts Spread Of H1N1
A new scientific system developed by a St. Michael"s Hospital physician, designed to rapidly evaluate the world"s air traffic patterns, accurately predicted how the H1N1 virus would spread around the world, according to research published in the New England Journal of Medicine.
News of the day
Senate Finance Committee Holds Second Closed-Door Meeting On Health Care Reform; Details Of House Energy And Commerce Committee Overhaul Plan Leaked
The Senate Finance Committee and the House Energy and Commerce Committee on Thursday both worked on health care proposals aimed at overhauling the U.S. health care system, CQ Today reports. In its second of three closed-door meetings, the Finance Committee came to "early, broad agreement" on some issues but continued to disagree over a public option as part of a reform bill. Meanwhile, portions of an overhaul plan being developed by the Energy and Commerce Committee were leaked on Thursday, after Democrats on the committee held a closed-door session on the topic earlier this week (Armstrong, CQ Today, 5/14). Finance Committee
Nutrition

The Downside Of Microtubule Stability - Study Shows Stalled Microtubules Might Be Responsible For Some Cases Of Charcot-Marie-Tooth Disease

Stalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth (CMT) disease, Tanabe and Takei report in the June 15, 2009 issue of the Journal of Cell Biology. A mutant protein makes the microtubules too stable to perform their jobs, the researchers find. The mutations behind CMT disease slow nerve impulses, reduce their strength, or both. One of these mutations leads to production of faulty dynamin 2, a protein that is crucial for endocytosis but also latches onto microtubules. Tanabe and Takei investigated how defective dynamin 2 hampers cells. Normal microtubules are continually extending and shrinking. But microtubules from cells that made the faulty version of dynamin 2 were abnormally stable, as measured by how many acetyl groups were attached to them. The researchers also found that blocking normal dynamin 2 with RNAi had the same effect as the mutation, confirming that one of dynamin 2"s functions is to promote microtubule turnover. Removing dynamin 2 shattered the Golgi complex, Tanabe and Takei discovered. Dynamic microtubules help construct the Golgi complex in two ways: they capture the vesicles that combine to form a mature Golgi complex; and they provide a track along which these vesicles can travel to their rendezvous point near the nucleus. By breaking up the Golgi apparatus and then watching the fragments reunite, the researchers found that dynamin 2 was essential for the capture step, not for transportation. Dynamin 2 also clings to microtubules of the mitotic spindle, and the team next wants to determine whether the protein regulates microtuble dynamics during the cell cycle. Notes: About the Journal of Cell Biology Founded in 1955, the Journal of Cell Biology (JCB) is published by the Rockefeller University Press. All editorial decisions on manuscripts submitted are made by active scientists in conjunction with our in-house scientific editors. JCB content is posted to PubMed Central, where it is available to the public for free six months after publication. Authors retain copyright of their published works and third parties may reuse the content for non-commercial purposes under a creative commons license. For more information, please visit http://www.jcb.org or visit the JCB press release archive at http://www.eurekalert.org/jrnls/rupress. Tanabe, K., and K. Takei. 2009. J. Cell Biol. doi:10.1083/jcb.200803153. Rita Sullivan Rockefeller University Press


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):

© Copyright 2009