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New Imaging Technique: Toward Spinal Cord Regeneration?
The axon is a part of the neuron through which nerve impulses are transmitted, and at the end of which is located the synapse, which connects it to another neuron. In the event of a lesion, the axon is the component which must be regenerated in order to restore the connections between the different neurons and re-form the nerve.
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Transmission Of Huntington's Disease To Offspring Among Male Carriers: Risk Estimated By Researchers
Researchers from Boston University School of Medicine (BUSM) have quantified the probability of a male who carries a "high normal" variant of the Huntington"s Disease (HD) gene having a child who develops the disease. Although thought to be a very rare event, the probability has never been estimated using current information and disease guidelines. The findings, appear on-line in the American Journal of Medical Genetics, may be useful during prenatal genetic counseling.
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MPS Clarifies Indemnity Arrangements For GPs During A Pandemic Flu Outbreak
Medical Protection Society (MPS) GP members, who are expected to work outside of their normal duties during a pandemic flu, should feel confident that they can turn to the MPS for assistance, in the event they are subject to a clinical negligence claim or other medicolegal matter such as a complaint.
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Two Types Of Urgency - Overactive Bladder - Urgency Is Not Just Urgency

UroToday.com - "Urgency" is the cornerstone of the diagnosis of overactive bladder (OAB) as well as a common complaint of patients with BPS/IC. What the term actually refers to when used by patients remains problematic and the subject of some controversy. The International Continence Society defines it as a "sudden compelling desire to void that is difficult to defer". The word sudden is designed to differentiate the sensation from the "urgency" that patients with BPS/IC complain of, but the distinction is quite vague in practice. Many believe that it is the reason for the urgency (fear of incontinence vs. pain) that should make the distinction. Dr. Jerry Blaivas and colleagues from New York City published an interesting study detailing the results of a survey administered to 48 consecutive patients who complained of urinary urgency. The survey was validated by administering 2 different questionnaires. Each group of 24 patients received one questionnaire twice (for test/retest reliability) and also received the other questionnaire. For questionnaire #1 the urge sensation was an intensification of the normal sensation for 68% of patients and it was a different sensation for 31%. For questionnaire #2, it was an intensification of the normal urge in 71% and different in 29%. In the crossover section only 1 of 48 subjects changed their response. Blaivas points out that some authors believe that urgency is like a light switch; it is either on or off and cannot be graded. It differs from urge, which is a normal physiologic sensation. This distinction has been based on expert opinion. The authors" data suggests that urgency is comprised of at least two different sensations in the OAB population. One is an intensification of the normal urge to void, and the other is an altogether different sensation. In the over two-thirds who experience the first type, grading of urgency should be possible and the light-switch theory would not hold. If one includes the urgency described by the BPS/IC patients, the situation becomes even more complex. One word may not do justice to what we or our patients are trying to describe, and better definitions and terminology may be required to facilitate a proper history and basic and clinical research studies. Blaivas JG, Panagopoulos G, Weiss JP, Somaroo C Neurourol Urodyn. 2009;28(3):188-90. doi: 10.1002/nau.20525 Written by UroToday.com Contributing Editor Philip M. Hanno, MD, MPH UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice. To access the latest urology news releases from UroToday, go to: www.urotoday.com Copyright © 2009 - UroToday


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