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Faster Protein Folding Achieved Through Nanosecond Pressure Jump
A new method to induce protein folding by taking the pressure off of proteins is up to 100 times faster than previous methods, and could help guide more accurate computer simulations for how complex proteins fold, according to research by a team of University of Illinois scientists accepted for publication in the journal Nature Methods and posted on the journal"s Web site May 31.
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Making Waves: LSU's WAVCIS Increases Modeling Capabilities
LSU"s WAVCIS, or Wave-Current-Surge Information System for Coastal Louisiana, has a few new tricks up its sleeve in preparation for the 2009 hurricane season.
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What Is High Blood Pressure? What Causes High Blood Pressure?
High blood pressure is also known as hypertension. Blood pressure is the amount of force exerted against the walls of the arteries as blood flows through them - if a person has high blood pressure it means that the walls of the arteries are receiving too much pressure repeatedly - the pressure needs to be chronically elevated for a diagnosis of hypertension to be confirmed. In medicine chronic means for a sustained period; persistent.
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UPCI Joins ExCell Research Study Using Stem Cells For Leukemia And Lymphoma Patients

The University of Pittsburgh Cancer Institute (UPCI) and the Gamida Cell - Teva Joint Venture announced today that the Institute has joined an elite group of cancer centers in Europe, the United States and Israel that are now enrolling patients to participate in the ExCell research study. The phase III study is assessing the safety and efficacy of StemEx®, an investigational product derived from stem cells, as an alternative treatment to bone marrow transplants for hematological malignancies, including leukemia and lymphoma. StemEx is a graft of expanded stem/progenitor cells taken from a single unit of umbilical cord blood and then transplanted in combination with non-expanded cells from the same unit. "I am extremely pleased UPCI has the opportunity to be a part of this study," said Mounzer Agha, M.D., clinical director of UPCI"s Hematopoietic Stem Cell Transplant Program. "Using umbilical cord blood stem cells instead of a traditional bone marrow transplant opens tremendous treatment possibilities for patients with diseases like leukemia and lymphoma." Bone marrow transplantation is a life-saving treatment for many types of leukemia and lymphoma. However, more than half the number of patients in need of a transplant can"t find matching bone marrow donors. Cord blood could be an alternative of choice. Previous research has shown that umbilical cord blood stem cells offer a viable therapeutic option for leukemia and lymphoma patients without the necessity of a matched donor. Umbilical cord blood has two important advantages-it is a readily available for stem cells and it has a lower matching requirement for patients. With StemEx®, the cord blood unit is enriched with stem cells, which are critical for a successful transplantation. "We are pleased to work with the able and highly experienced team at UPCI led by Dr. Agha. They join an extraordinary group of cord blood cancer centers currently recruiting patients for the ExCell trial. Everyone on the international ExCell clinical team shares the same goal-to validate the therapeutic potential of StemEx as a treatment for blood cancers," said David Snyder, M.D., vice president of clinical development at Gamida Cell. The University of Pittsburgh Cancer Institute


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