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"Artificial Golgi" May Provide New Insight Into Key Cell Structure
Scientists in New York and North Carolina are reporting assembly of the first functioning prototype of an artificial Golgi organelle. That key structure inside cells helps process and package hormones, enzymes, and other substances that allow the body to function normally. The lab-on-a-chip device could lead to a faster and safer method for producing heparin, the widely used anticoagulant or blood thinner, the researchers note. Their study is scheduled for the Aug. 12 issue of the Journal of the American Chemical Society, a weekly publication.
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RCN Responds To New Report Into Nursing Regulation
Responding to the annual report from the Council for Healthcare Regulatory Excellence (CHRE), Dr. Peter Carter, Chief Executive & General Secretary of the Royal College of Nursing (RCN), said:
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Discovery Of Gene Mutation Responsible For Hereditary Neuroendocrine Tumor
University of Utah researchers and their colleagues have identified the gene that is mutated in a hereditary form of a rare neuroendocrine tumor called paraganglioma (PGL). The gene, called hSDH5, is required for activation of an enzyme complex that plays a critical role in the chemical reactions that take place within cells to convert biochemical energy into usable energy. This study is published in the journal Science
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WorldCare Clinical Implements MCC's Imaging Performance Metrics In Support Of Standardized Peformance For Imaging Trials

45th DIA Annual Meeting -- Booth # 1501 -- WorldCare Clinical, LLC (WCC), a leading imaging CRO for clinical trials in the pharmaceutical, biotechnology and medical device industries, announced that it is offering version 1.0 of the Metrics Champion Consortium (MCC) Imaging Performance Metrics to all sponsors" imaging trials beginning July 1, 2009, through its WorldPro™ technology solution. "We are pleased to announce that WCC is implementing the MCC Imaging Performance Metrics," said Dr. Asli Memisoglu, director of biostatistics and data management at WCC. "Through our innovative WorldPro technology platform, WCC is committed to support industry-wide acceptance of MCC"s performance metrics to help ensure best outcomes for our sponsors." The MCC Imaging Performance Metrics Work Group is a non-profit organization made up of biotechnology, pharmaceutical and service provider organizations that work collaboratively to develop and implement standardized performance metrics aimed at improving the efficiency and effectiveness of managing and tracking res needed to successfully run clinical trials. Additionally, WCC will offer statistical analysis of reader reliability, with metrics such as kappa and correlation coefficients, to evaluate reader performance and reliability. "It is critical for a study"s success to have a high level of agreement across readers and good consistency within assessments made by the same reader," said Dr. Richard Walovitch, chief medical officer at WCC. "WCC provides the results from these ongoing evaluations to the client and the reading team in the form of a study newsletter, which helps to facilitate communication of case studies, reader performance, and operational metrics." WCC representatives will be available at Booth # 1501 during this week"s DIA Annual Meeting in San Diego, California, to discuss its application of the MCC and other metrics in imaging trials. For more information or to schedule an appointment, contact Vanessa Conde at (978) 406-5518 or vconde@wcclinical.com. WorldCare Clinical


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