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Study Offers New Insights Into Morphine-Induced Tolerance And Increased Pain Sensitivity
A study published in the June issue of Anesthesiology has shown that a drug metabolite of the opioid morphine may be a key factor in the paradoxical increased sensitivity to pain caused by chronic morphine use. For the first time, this metabolite (called morphine-6 glucuronide, or M6G) was shown to act independently of the pain receptors typically targeted during morphine administration.
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Unexpected Bacterial Diversity Found On Human Skin
The health of our skin - one of the body"s first lines of defense against illness and injury - depends upon the delicate balance between our own cells and the millions of bacteria and other one-celled microbes that live on its surface. To better understand this balance, National Institutes of Health researchers have set out to explore the skin"s microbiome, which is all of the DNA, or genomes, of all of the microbes that inhabit human skin. Their initial analysis, published in the journal Science, reveals that our skin is home to a much wider array of bacteria than previously thought.
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SAMe Is Effective In Preventing Formation Of Primary Liver Cancer In Rats
A new study investigated the effectiveness of S-adenosylmethionine (SAMe) in the prevention and treatment of hepatocellular carcinoma (HCC) or primary liver cancer. SAMe, a widely available nutritional supplement, with little known side effects, was found to be effective in preventing the formation of HCC in rats. However, high enough levels of SAMe were not attainable to successfully treat established HCC. The findings are available in the August issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases.
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Would You Know What To Do In A Mental Health Emergency?

A quarter of us will experience at least one mental health problem in any one year, and yet stigma and prejudice are still widespread. In recognition of this hidden health crisis, The Royal Society for Public Health has accredited the Mental Health First Aid (MHFA) training programme in England, developed to establish a network of people with the skills and knowledge to take this essential first aid training into the community. Mental health problems can affect people at any time, in different ways, and many suffer in silence for a long time before eventually seeking help. The MHFA course trains people to recognise the symptoms of mental health problems, shows how to offer initial help to those affected, and provides information about professional support. MHFA supports the government"s well-being agenda which highlights the importance of early intervention. Trainees on mental health first aid courses work in many different settings, including commercial organisations, teaching, police and prison services. Fionuala Bonnar, programme director for Mental Health Services and Improvement, London Development Centre, part of Commissioning Support for London, said: "The MHFA course instructors are a vital link in our work to promote awareness of mental health problems. RSPH accreditation for our instructors" programme shows that our courses are delivered to the RSPH"s very high standards, giving additional confidence to instructors, trainees and the public." RSPH chief executive professor Richard Parish comments: "Many people are familiar with first aid for physical health, but there is a much more limited understanding of first aid for mental health. Early recognition of mental health problems can make all the difference to the outcome for individuals and their families, and the mental health first aid course gives trainees the practical knowledge to help identify anyone who may need professional help. Excellent training for these instructors is essential to the success of this much needed work. RSPH accreditation confirms the high quality of the instructor training programme and I congratulate all those involved in achieving this recognition." Notes 1.The Royal Society for Public Health (RSPH) is an independent, multi-disciplinary organisation, dedicated to the promotion and protection of collective human health and wellbeing. Through advocacy, mediation, empowerment, knowledge and practice, it advises on policy development, provides education and training services, encourages scientific research, disseminates information and certifies products, training centres and processes. A registered charity that enjoys patronage of Her Majesty the Queen, RSPH is the oldest public health body in the world, with over 150 years" experience in its field of protecting and promoting public health. 2. The National Mental Health Development Unit (NMHDU) MHFA was originally developed in Australia and has been adapted for use in England by NMHDU. More than 100 MHFA instructors have now been trained. The RSPH"s accreditation scheme is designed to endorse training programmes that support health, hygiene and safety. The MHFA instructor training programme has undergone an expert review, assessing how effectively it prepares potential instructors to deliver MHFA courses to trainees responsible for staff health and wellbeing. For more information on Mental Health First Aid training programmes and instructor courses, please visit http://www.mhfaengland.org.uk Royal Society for Public Health


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