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Safe New Treatment Combination For Head And Neck Cancer Patients
Patients undergoing treatment for advanced head and neck cancers may respond well to the addition of gefinitib to chemotherapy, according to a study sponsored by the Eastern Cooperative Oncology Group and chaired by Ethan Argiris, M.D., associate professor of medicine, University of Pittsburgh School of Medicine, and co-leader of the Head and Neck Cancer Program of the University of Pittsburgh Cancer Institute (UPCI). The results were disclosed at the 45th annual meeting of the American Society of Clinical Oncology (ASCO) on May 30 in Orlando, Fla.
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ReachMD Launches CME iPhone APP
ReachMD, which provides medical news and information to healthcare practitioners, is raising its profile with the Continuing Medical Education, or CME, application for the Apple iPhone and iPod touch. This is the first CME application that lets users listen to all ReachMD Continuing Medical Education content, get regular updates on new Continuing Medical Education content and take Continuing Medical Education tests for credit, all from their iPhone or iPod touch.
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Congress Should Not Restrict Use Of Local Funds For Abortion Funding In D.C., Washington Post Editorial States
During debate on the fiscal year 2010 appropriations bill for Washington, D.C., some House members on Tuesday "are expected to use the opportunity to introduce provisions that limit how the district may use locally derived funds," including funding for abortion services, a Washington Post editorial states. "These efforts are wrong, infringe on the district"s right to self-rule and should be voted down," the editorial adds.According to the editorial, "For years, the district has labored under a provision that prevents it from using local tax dollars to fund or subsidize abortion services." The editorial notes that the "Hyde Amendment already forbids state and local jurisdictions from using federal money for abortion services, but it does not restrict these entities from using local tax dollars."A House subcommittee last month approved $768 million in federal funds for D.C., but Rep. Jose Serrano (D-N.Y.) -- chair of the subcommittee -- "stripped the abortion provision from the appropriations bill," according to the editorial. It continues that this version of the bill is "now before the full House Appropriations Committee," and "[s]ome abortion foes in the House plan to reintroduce the abortion-funding restriction."The editorial states, "Federal lawmakers have the right to seek limits on how federal money is used, but not to impose those same limits on states." It concludes that D.C. "should be treated with the same respect afforded every other sovereign jurisdiction in the country" (Washington Post, 7/7).
Public Health

fMRI Study Can See The Emotions

By observing the pattern of activity in the brain, scientists have discovered they can "read" whether a person just heard words spoken in anger, joy, relief, or sadness. The discovery, reported online on May 14th in Current Biology, a Cell Press publication, is the first to show that emotional information is represented by distinct spatial signatures in the brain that can be generalized across speakers. "Correct interpretation of emotion in the voice is highly important - especially in a modern environment where visual emotional signals are often not available," for instance, when people talk on the phone, said Thomas Ethofer of the University of Geneva, Switzerland. "We demonstrated that the spatial pattern of activity within the brain area that processes human voices contains information about the expressed emotion." Previous neuroimaging studies showed that voice-sensitive auditory areas activate to a broad spectrum of vocally expressed emotions more than to neutral speech melody, the researchers explained. However, this enhanced response occurs irrespective of the specific category of emotion, making it impossible to distinguish different vocal emotions with conventional analyses. In the new study, the researchers presented people with pseudowords spoken in five ways - with anger, sadness, relief, joy, or no emotion - while their brains were scanned with functional magnetic resonance imaging (fMRI). They then analyzed the overall spatial pattern of activity in the auditory cortex by using a method called multivariate pattern analysis. "While conventional methods analyze each point in the brain separately, we looked at the overall pattern," Ethofer explained. "Consider the following analogy: If you have a puzzle consisting of black and white pieces, it is hard to say whether they belong to a picture of a zebra or a checkerboard if you look at each piece in isolation, but it becomes relatively easy if you put the pieces together." Indeed, their analysis showed that they could classify each emotion against all other alternatives. The findings have not only yielded new insight into this most critical of social skills, but they might also help researchers unravel where it goes wrong in those with various psychiatric disorders, Ethofer said. "Comprehension of emotional prosody is crucial for social functioning and compromised in various psychiatric disorders, including deficits for anger and sadness in schizophrenia, fear and surprise in bipolar affective disorder, and surprise in depression," the researchers wrote. "Future research might apply a similar approach as ours to clarify whether these deficits are paralleled by activity changes blurring emotions at the level of auditory cortex, or are due to disrupted patterns within frontal regions reflecting biased interpretation of emotional signals." Cathleen Genova Cell Press


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