Medical Devices
MetLife, providing dental plan administration for over 21 million people, announced additions to its dental continuing education program today. Three new quality re guides have been added to the MetLife program, which is recognized by the American Dental Association (ADA) and the Academy of General Dentistry (AGD). The new courses focus on: 1) Assessing Orofacial Pain, 2) Assessing Risk for Chronic Periodontitis in Adults 3rd Edition, and 3) Recognition and Management of Patients with Xerostomia 2nd Edition. The courses are available online at http://www.metdental.com and can be completed for continuing education credits.
National Community Pharmacists Association (NCPA) Executive Vice President and CEO, Bruce T. Roberts, RPh testified today before the U.S. House Energy and Commerce Subcommittee on Health, offering four different recommendations to strengthen a health care reform proposal currently working its way through Congress.
Vision loss costs Canadian society a staggering $15.8 billlion per year - significantly higher than previously estimated, according to new research study released on June 23, 2009, by CNIB and the Canadian Ophthalmological Society (COS). The study"s proponents say these costs, which are expected to increase dramatically in the years ahead, underscore the urgent need for Canada to develop a comprehensive national vision health plan.
An election date has now been set for July 21 and 22 in the campaign by registered nurses at HCA"s MountainView Hospital in Las Vegas to be represented by the California Nurses Association/National Nurses Organizing Committee, the nation"s pre-eminent professional association and union for RNs.
The American Psychiatric Association (APA) commended
"A bipartisan group of governors told President Obama yesterday that they share his urgent desire to restructure the nation"s health-care system but warned that any changes should not place more burdens on strained state budgets or eliminate innovative programs they already have in place," The Washington Post reports. "With many state budgets burdened by ballooning... Medicaid costs, the five governors who met with Obama at the White House agreed that changes are needed to expand health-care coverage and contain its costs." But they were also "adamant that the restructuring of the health-care system not push new costs on states. "If we"re going to add more population onto the Medicaid rolls, there has to be a way to pay for that," said Gov. Jennifer M. Granholm, D-Mich., adding that it is a position Obama supported." Republican governors Jim Douglas of Vermont and Mike Rounds of South Dakota, and Democrats Granholm, Jim Doyle of Wisconsin and Chris Gregoire of Washington, attended the meeting (Fletcher, 6/25).
The number of people killed at work in Britain has fallen to a record low, new figures from the Health and Safety Executive (HSE) reveal.
The New York Times examines a program being offered at an orphanage in Tanzania that provides emotional and physical support for newborns and young children who are at a high risk of death after losing their mothers in infancy. "Africa is full of at least 50 million orphans, the legacy of AIDS and other diseases, war and high rates of death in pregnancy and childbirth," the newspaper writes. "With the numbers increasing every day, Africans are struggling to care for them, often in ways that differ strikingly from the traditional concept of an orphanage in the developed world."
The H1N1 (swine flu) virus has reached the sub-Saharan African countries of Cape Verde, Ethiopia and Ivory Coast, according to the WHO, the AP/Boston Herald reports. Last week, South Africa became the first country in the region to confirm a 12-year-old, who had returned from the U.S., tested positive for the H1N1 virus.
The full U.S. Court of Appeals for the 4th Circuit in a 6-5 decision on Wednesday upheld Virginia"s 2003 law banning what abortion-rights opponents call "partial-birth" abortion, a procedure known medically as intact dilation and extraction, the AP/Hartford Courant reports (O"Dell, AP/Hartford Courant, 6/24). In 2005, a three-judge panel of the U.S. Court of Appeals for the 4th Circuit ruled 2-1 to strike down the Virginia law on the grounds that it does not include adequate exceptions to protect a woman"s health. The U.S. Supreme Court two years ago ordered the appeals court to revisit the issue when it upheld the Partial Birth Abortion Ban Act of 2003, a federal law similar to the Virginia law (White, Washington Post, 6/25). The three-judge appeals panel again struck down the law in 2008 (AP/Hartford Courant, 6/24). The Virginia law permits women to choose various abortion procedures but makes it a crime for providers to perform an intact dilation and extraction, which involves crushing a fetus" skull to ease removal (Washington Post, 6/25). Abortion-rights supporters said that the Virginia law is unconstitutional because its broad definition of intact dilation and extraction could also prohibit standard dilation and extraction, the more common form of second-trimester abortion. Violations of the law would be considered a felony and punishable by up to 10 years in prison. The case is Richmond Medical Center v. Herring (AP/Hartford Courant, 6/24). William Fitzhugh, the Richmond doctor who challenged the Virginia law, said that the banned procedure is necessary to protect the life of the woman in some cases and that the law could prevent abortion providers from performing legal procedures out of fear of prosecution. Stephanie Toti, a Center for Reproductive Rights attorney who represented the plaintiffs, said that the Virginia law is broader than federal law because it punishes abortion providers who accidentally violate the law while performing legal abortion procedures. Judge"s Opinions Judge Paul Niemeyer in the majority opinion wrote that Virginia law protects physicians who are taking needed steps to save a patient"s life and should prevent "a Morton"s fork, where the doctor must choose between criminal liability or care that the doctor believes is not in the best interest of the patient." He added that the circumstances in which doctors could face criminal liability are so limited that they should not invalidate the law in every other case. Judge Blane Michael wrote in the dissenting opinion that the law will create a "real fear of criminal liability" among physicians because it will have the effect of criminalizing the actions of those who seek to perform legal procedures but need to use the banned procedure in rare instances. Michael wrote that the law therefore "places an undue burden on a woman"s right to obtain a pre-viability second trimester abortion -- a constitutional right repeatedly reaffirmed by the Supreme Court" (Washington Post, 6/25).Next StepsToti said that no decision has been made on whether to appeal the decision to the Supreme Court. The Supreme Court"s 2007 decision on the federal law made it clear that abortion bans must include exceptions for the health of the woman, the AP/Hartford Courant reports. Toti said that the appeals court"s decision "just really ignores that precedent." She added, "It"s really insulting to women"s dignity that the court would put so little priority on protecting women"s health and well-being" (AP/Hartford Courant, 6/25). Toti also said, "It puts doctors in a really untenable position because it forces doctors to choose between taking all the steps necessary to protect their patients and committing a felony" (Washington Post, 6/25). Virginia Attorney General Bill Mims said, "While we anticipate that the U.S. Supreme Court may be asked to review the decision, I am confident that the Supreme Court ultimately will uphold the law" (AP/Hartford Courant, 6/25).
Researchers have successfully blocked SIV, the simian version of HIV, using a new technique that could help lead to the development of an effective HIV/AIDS vaccine, the reports. The research, published online in the journal Nature Medicine, was led by Phillip Johnson, chief medical officer at the Children"s Hospital of Philadelphia. The team also included scientists from Nationwide Children"s Hospital in Columbus, Ohio, and the New England Primate Research Center in Boston.Johnson and colleagues developed a genetically altered virus that carried the vaccine candidate and injected it into the muscles of monkeys. The vaccine prompted the muscles to produce a protein that is designed to bind to SIV and prevent it from infecting cells (Goldstein, Philadelphia Inquirer, 5/18). After treating nine monkeys with the vaccine candidate for one month, the researchers injected them with SIV. Six monkeys were not administered the vaccine candidate before being injected with SIV. None of the immunized monkeys developed AIDS, while three showed indications of SIV infection. Researchers detected high concentrations of the proteins in their blood one year later. All six non-immunized monkeys became infected with SIV, and four died during the trial (Schmid, AP/Austin American-Statesman, 5/18). The DNA used in the carrier virus can deliver DNA into the cells of both monkeys and humans, according to the Inquirer. Johnson said that the results of the trials were so encouraging that he plans to request approval from FDA to begin clinical trials in humans, the Inquirer reports. However, he said that there is "no guarantee that things that work in monkeys will work in humans," adding that an HIV/AIDS vaccine could be 10 years away (Philadelphia Inquirer, 5/18). Recent HIV/AIDS vaccine failures prompted the researchers to try a different route that involved "bypassing the natural immune system that was the target of all previous HIV and SIV vaccines candidates," Johnson said. "Some years ago I came to the conclusion that HIV was different from other viruses ... and we might not ever be able to use traditional approaches," he added (AP/Austin American-Statesman, 5/18). Peggy Johnson -- head of the HIV Vaccine Research Branch at NIH"s National Institute of Allergy and Infectious Diseases, which helped fund the study -- said, "As a concept, I think this is very promising." She added, "We need to make the genes as humanized as possible so that the human body doesn"t react to that." According to Peggy Johnson, tests will be needed to prove that the vaccine candidate can protect against sexually acquired HIV (Fox, Reuters, 5/17). Beatrice Hahn, an HIV/AIDS researcher with the University of Alabama-Birmingham, said that the study"s findings indicate that there is "a light at the end of the tunnel," adding, "It shows thinking outside the box is a good idea and can yield results, and we need perhaps more of these nonconventional approaches" (AP/Austin American-Statesman, 5/18). Hildegund Ertl, a virus expert at the Wistar Institute in Philadelphia, said, "It is a very innovative approach but currently, in my mind, still far from clinical use." Ertl added that because most people have been exposed to adeno-associated viruses through cold viruses, they would be "likely to mount an immune response" to the vaccine. According to Phillip Johnson, most people have not been exposed to the strain of the adeno-associated virus that the researchers used as the carrier. He added that they "will be certainly looking at that as part of our Phase I testing in humans" (Philadelphia Inquirer, 5/18).
The National Institute for Health and Clinical Excellence (NICE) has published guidance on cetuximab for the treatment of recurrent and/or metastatic (where the cancer has spread) squamous cell cancer of the head and neck. The guidance does not recommend cetuximab in combination with platinum- based chemotherapy as a treatment option for patients with this type of head and neck cancer.
People in very early stages of Alzheimer"s disease already have trouble focusing on what is important to remember, a UCLA psychologist and colleagues report.
A quarter of us will experience at least one mental health problem in any one year, and yet stigma and prejudice are still widespread.
If you have hay fever, headaches or a cold, it"s only a short way to the nearest chemist. The drugs, on the other hand, can take eight to ten years to develop. Until now animal experiments have been an essential step, yet they continue to raise ethical issues. "Our artificial organ systems are aimed at offering an alternative to animal experiments," says Professor Heike Mertsching of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart. "Particularly as humans and animals have different metabolisms. 30 per cent of all side effects come to light in clinical trials." The test system, which Professor Mertsching has developed jointly with Dr. Johanna Schanz, should in future give pharmaceutical companies greater security and shorten the path to new drugs. Both researchers received the "Human-centered Technology" prize for their work.
Scientists at the Gladstone Institutes of Virology and Immunology (GIVI) have found another clue that may lead to eradication of HIV from infected patients who have been on antiretroviral therapy. A real cure for HIV has been elusive because the virus can "hide" in a latent form in resting CD4-T cells. By understanding this "latency" effect, researchers can identify ways to reactivate the virus and enable complete clearance by current or future therapies.
Veritide Ltd., a developer of innovative biological identification and detection solutions, today reported that new independent data to be presented at the Biodetection Technologies 2009 conference confirm the exceptional accuracy of its Ceeker™ (pronounced "seeker") portable bacterial detection device in discriminating between anthrax spores and similar-looking hoax substances. The data show that in over two weeks of testing at the Midwest Research Institute in Florida, the company"s Ceeker scanner accurately identified 100% of the anthrax samples used and was correct in 95% of tests involving hoax substances. These test results are consistent with similar results produced last year by a New Zealand forensic testing agency, Environmental Science and Research (ESR).
Contrary to predictions, males of high genetic quality are not very successful when it comes to fertilizing eggs. A new study on seed beetles by Swedish and Danish scientists Goran Arnqvist and Trine Bilde shows that when a female mates with several males, the males of low genetic quality are the most successful in fertilizing eggs. The study is published in this week"s issue of Science.
The recent decline in invasive breast cancer in the US was significantly less pronounced in the poor and those who live in rural areas. Researchers writing in the open access journal BMC Medicine suggest this may be due to varying reductions in the numbers of women taking hormone therapy (HT).
Researchers at the Yerkes National Primate Research Center, Emory University, have demonstrated for the first time rhesus monkeys and humans share a specific perceptual mechanism, configural perception, for discriminating among the numerous faces they encounter daily. The study, reported in the June 25 online issue of Current Biology, provides insight into the evolution of the critical human social skill of facial recognition, which enables us to form relationships and interact appropriately with others.
HearAtLast Holdings, Inc. (PINKSHEETS: HRAL), a leading provider of suitable affordable solutions to clients with hearing needs in the billion dollar hearing loss market, announced that in keeping with its tradition of bringing innovative new products to consumers, the Company announces the unveiling of breakthrough hearing products based on the Neuro-Compensator™ algorithm technology from VitaSound Audio.
An article published Online First and in this week"s edition of reports information about Golimumab, a new tumour necrosis factor-í± (TNF-í±) inhibitor. It reduces the signs and symptoms of rheumatoid arthritis in patients who have previously received any other TNF-í± inhibitor. This drug might be a good alternative for patients who have inadequate responses to one or two other TNF-í± inhibitors.
Some senators on the Finance Committee said Thursday they"ve moved closer to cutting their health reform bill"s cost to under $1 trillion.
Entomopathogenic fungi may be a safe and efficient means of controlling
The Associated Press/Washington Post reported that U.S. health officials on Thursday said they believe as many as 1 million Americans have been infected with H1N1 and "6 percent or more of some urban populations are infected." The estimates were based upon survey data collected by health officials and mathematical modeling.
Many people who test positive for HIV are diagnosed late in the course of their infection when treatment might be less effective, according to a report published Thursday in CDC"s Morbidity and Mortality Weekly Report, Reuters Health reports. The report looked at data on people who were diagnosed with HIV from 1996 to 2005 and found that 45 percent had developed AIDS within three years of their initial HIV diagnosis, 38.3 percent within one year and an additional 6.7 percent within the next two years (Reuters Health 6/25). R. Luke Shouse of CDC"s Division of HIV/AIDS Prevention in the National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, said, "This means that they may have unknowingly transmitted HIV. It also means that there is a time when they had HIV when they were not under appropriate medical care, so there are missed opportunities for prevention and care." A separate CDC report also published yesterday found that 22.3 percent of high school students who are sexually active and 12.9 percent of all students have been tested for HIV (Reinberg, HealthDay/KATC.com, 6/25).
July 1, 2009
The risk of cancer possibly increases if patients with diabetes use the long-acting insulin analogue glargine instead of human insulin. The Institute for Quality and Efficiency in Health Care (IQWiG), in collaboration with the "Wissenschaftliches Institut der AOK" (WIdO), the research institute of the German Local Health Care Fund, analysed the data of almost 130,000 patients with diabetes in Germany who had been treated with either human insulin or the insulin analogues lispro (trade name: Humalog), aspart (Novorapid) or glargine (Lantus) between January 2001 and June 2005.
The efficacy of preimplantation genetic screening (PGS) has been one of the most hotly disputed subjects in assisted reproduction over the past few years. None of the trials carried out so far has shown conclusively whether it works or not. Now the European Society of Human Reproduction and Embryology (ESHRE) Task Force on PGS has decided to try to find out if a novel method of doing PGS using polar body biopsy and chromosome array analysis offers a possible solution.
In one of the most field-intensive efforts to explore the connection between malaria and tropical deforestation, a team led by Jonathan Patz, a specialist in the link between environment and health at the Nelson Institute for Environmental Studies at the University of Wisconsin-Madison, has established a strong correlation between the extent of forest destruction and the incidence of the Amazon"s most dangerous malaria vector, the mosquito Anopheles darlingi.
GI Dynamics, a leader in non-surgical treatments for type 2 diabetes and obesity, today announced results from a pilot clinical study which demonstrated the substantially enhanced weight loss effects of combining the company"s EndoBarrier Gastrointestinal Liner with a new EndoBarrier Flow Restrictor. The EndoBarrier Flow Restrictor provides an adjustable restriction at the outlet of the stomach and is designed to delay gastric emptying, an additional mechanism which adds to the therapeutic effects of the liner. The results were presented today at the 26th annual meeting of the American Society for Metabolic and Bariatric Surgery (ASMBS).
Over the last five days, the Middlesex-London Health Unit has received reports of three children with E. coli O157:H7. To receive three laboratory confirmed cases of E. coli O157:H7 in such a short timeframe is unusual. In two of these cases, the common food consumed was kofta (spiced ground beef) purchased on June 14 and 15 from the Westmount Halal Food Store located at 490 Wonderland Road South. The of the third child"s infection is currently unknown. This child"s family also eats halal food but did not purchase any food from the Westmount Halal Food Store.
The number of local health services implementing NICE"s fertility guideline and offering three cycles of IVF treatment to couples who are unable to conceive naturally has increased significantly in the past year, according to a new survey published by the Department of Health. According to these new figures, more than a quarter of primary care trusts now offer the full number of cycles recommended by NICE- this figure is up from five per cent in 2007.
Exercise and electro-acupuncture treatments can reduce sympathetic nerve activity in women with polycystic ovarian syndrome (PCOS), according to a new study. The finding is important because women with PCOS often have elevated sympathetic nerve activity, which plays a role in hyperinsulinemia, insulin resistance, obesity and cardiovascular disease
Legislation to create smokefree public places has been named as the most important policy implemented by the Scottish Parliament in the 10 years since devolution, according to a survey of Scottish doctors conducted by BMA Scotland. The results of the survey mark the publication of a new BMA Scotland newsletter yesterday (Monday 29 June) to celebrate 10 years of devolution and the creation of policy making powers for health in Scotland. Also featuring in the most popular policies to be implemented in Scotland were: ending the internal market in healthcare where GPs and hospitals compete to provide services, introducing free personal care and fee free education.
Physio-Control Inc., a wholly-owned subsidiary of Medtronic, Inc. (NYSE: MDT), announced today that LUCAS™ 2, the next-generation LUCAS™ Chest Compression System, has been granted 510(k) market clearance by the U.S. Food and Drug Administration (FDA). Developed and manufactured by Jolife AB and distributed exclusively in the United States by Physio-Control, the LUCAS 2 is an automated, battery-powered device that is designed to give consistent, uninterrupted compressions to victims in cardiac arrest.
IDF, WHF and UICC join forces
Complications in early pregnancy or in previous pregnancies can predict the likelihood of further problems in current or subsequent pregnancies, according to research carried out by an international group of experts.
A research article published in the World Journal of Gastroenterology addresses this question. This is believed to be the first study to investigate the effect of PBD in ampullary cancer. A team of gastroenterologists led by Dr Steven Joseph Mesenas and hepatobiliary surgeons at Singapore General Hospital divided 82 patients with ampullary cancer planned for surgical resection into those with PBD (n = 35) and those without (n = 47). The authors looked into various outcomes after surgery, such as pancreatic leakage, wound infection, bile leakage, infectious morbidity, intra-abdominal or gastrointestinal bleeding, intra-abdominal abscess, delayed gastric emptying and mortality. They found that the PBD group had a significantly reduced wound infection rate compared to the non-PBD group. More studies should be conducted to assess this benefit, especially in ampullary cancer patients.
A research article published in the World Journal of Gastroenterology refers. The research team lead by Dr. Gabriela Beatriz Acosta, observed that the activity of GS was increased in the hippocampus in PH rats. There was a significant decrease in glutamate uptake in both brain areas, which was more marked in the hippocampus. The decrease in glutamate uptake might be caused by deficient transport function and persistent glutamate activity, which is not metabolized. This leads to severe damage in the cells of the central nervous system (CNS), associated with the presence of moderate ammonia concentration in the blood, as observed in this model. These results demonstrated that partial stricture of the portal vein is able to modify normal function in important areas of the rat brain.
MVP® (Managed Ventricular Pacing), exclusive programming on Medtronic pacemakers, which is proven to be effective in reducing unnecessary pacing in pacemaker patients, was applied in the MVP Trial of implantable cardioverter-defibrillator (ICD) patients. Data from MVP trial, sponsored by Medtronic, Inc. (NYSE: MDT), were presented today as a late breaking clinical trial at Heart Rhythm 2009, the annual scientific sessions of the Heart Rhythm Society.
Medicare beneficiaries" activities of daily living (ADL) improved in their first year of the Medicare Part D senior prescription drug plan, according to a ground-breaking study presented at the Annual AcademyHealth meetings in Chicago today.
Massachusetts-based Catholic hospital system Caritas Christi Health Care on Friday ended its joint venture with the Missouri-based health insurer Centene after Cardinal Sean O"Malley of the Archdiocese of Boston insisted that the relationship linked Catholic hospitals too closely to abortion providers, the AP/San Francisco Chronicle reports (AP/San Francisco Chronicle, 6/27). Under the joint venture, Caritas and Centene created a new company, CeltiCare, which would have insured thousands of low-income Massachusetts residents under Commonwealth Care, the state"s subsidized health care program. Financially troubled Caritas, which was founded by the Archdiocese of Boston, said it will continue to participate as a provider in Commonwealth Care but will no longer be a co-owner of the insurance venture with Centene. Caritas will provide care to patients covered by Centene, as it does for patients covered by other private insurers, but it will not provide any services that violate Catholic teachings, such as abortions or sterilizations. In terminating the joint venture, the archdiocese hopes to appease criticism that Caritas would have profited from abortion and other services provided at non-Catholic medical centers, the Boston Globe reports. According to the archdiocese, O"Malley sought the withdrawal after weeks of consultation with the church-affiliated think tank National Catholic Bioethics Center, in response to harsh criticism from antiabortion-rights groups for not blocking the agreement. The withdrawal is "a vindication of sorts" for O"Malley"s critics, who have argued that it would be wrong for Caritas to enter an agreement with a health insurer that covers abortion care, according to the Globe. Andrea Miller, the executive director of NARAL Pro-Choice Massachusetts, said that Caritas" involvement in the joint venture had raised concern from NARAL because of the Catholic Church"s opposition to abortion rights. She said that although Caritas has withdrawn from the venture, "[t]he question remains: Will the involvement of Caritas Christi health providers negatively affect women"s ability to get timely access to reproductive services, including birth control?" Miller added that NARAL hopes that state regulators "will continue due diligence to ensure that referrals and services are provided in a manner that does not delay access to reproductive health services" (Paulson/Lazar, Boston Globe, 6/27).
The White House remains open to taxing some health benefits to help pay for health care reform despite campaigning against the move last year, The Washington Post reports.
Reuters reports that "President Barack Obama"s drive to overhaul the U.S. healthcare system may be back on track thanks to Senate efforts to cut the price tag to $1 trillion, but a bipartisan deal on the sweeping proposal still is far from certain ... Senate Finance Committee Chairman Max Baucus was upbeat last week after announcing that panel members had found ways to bring the price tag to about $1 trillion over 10 years, down from an earlier estimate of a staggering $1.6 trillion ... Instead, the core group of negotiators -- three Democrats and four Republicans -- issued a tepid statement on Thursday merely affirming their commitment to continue negotiations."
The Retail Advisory Board (RAB) of the National Association of Chain Drug Stores (NACDS) met yesterday during the 2009 NACDS Marketplace Conference to discuss social networking opportunities within their businesses.
MicroRNAs are small RNA molecules of 20-25 nucleotides length, regulating gene expression by inhibition of transcription or translation of proteins. High levels of miR-196a, a microRNA suppressing the expression of specific homebox genes that are of high relevance for the development of the human embryo, activated oncogenic pathways inside human tumor cells and induced tumor cell dissemination. miR-196a increased the chemosensitivity towards platin derivatives such as cisplatin and oxaliplatin and might be a useful biomarker.
A groundbreaking study to be published in the Journal of the American Veterinary Medical Association (JAVMA) shows that furosemide does more than enhance performance in Thoroughbred racehorses; it also has beneficial effects on the health and welfare of those horses.
Scientists at Queen Mary, University of London have discovered that an ingredient in human breast milk protects and repairs the delicate intestines of newborn babies.
The first three guides - Clinical Engagement, Governance and Prioritising Investment - will be launched at the Practice Based Commissioning National Forum, on 1 July. A fourth guide, on Patient and Public Engagement, will be published over the summer and a fifth, on Procurement, is already in the pipeline and expected to be published in September.
The Royal Pharmaceutical Society of Great Britain (RPSGB) has welcomed the appointment of Mr Robert Nicholls CBE as the Chair Designate of the General Pharmaceutical Council (GPhC).
Today the Lance Armstrong Foundation and the American Cancer Society announced they have formed a first-of-its-kind partnership to empower and support survivors all over the world and aggressively address the global cancer burden. As part of its ongoing global commitment to fight cancer, the Society has become an international collaborating partner for the LIVESTRONG® Global Cancer Summit in Dublin, Ireland in August. The Society will actively participate in LIVESTRONG Global Cancer Campaign events at both the Tour de France in July and the Summit, beginning Aug. 24 in Dublin. John R. Seffrin, Ph.D., chief executive officer, American Cancer Society, will join the U.S. delegation to the Summit and address the 250 advocates selected from all over the world for their commitments to cancer control.
Achaogen, a clinical stage biopharmaceutical company addressing the issue of multi-drug resistant bacterial infections through the discovery and development of innovative broad-spectrum antibiotics, announced today the presentation of research on aminoglycoside (AG) resistance trends and comparative AG toxicities at the 19th Annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), being held May 16-19, 2009 in Helsinki, Finland.
"Epidemiology is always important and topical, though sometimes unsung," says Professor Johan Giesecke, Chief Scientist at ECDC, the European Centre for Disease Prevention and Control, "but the third applied Infectious Disease Epidemiology Conference in Stockholm in October this year will be an opportunity to put Epidemiology and infectious disease prevention and control into the spotlight; delegates will have the opportunity to discuss and share information on current and emerging infectious diseases, including influenza A (H1N1)v. The call for abstracts closes on July 3rd so there is no time to lose."
Centocor Ortho Biotech Inc. announced today that a federal jury has returned a verdict of $1.67 billion against Abbott Laboratories in a patent infringement suit.
To be properly diagnosed, retinopathy of prematurity (ROP), the leading cause of childhood blindness in the United States and worldwide, requires a time intensive process and significant coordination between ophthalmologist and NICU staff. A recent study examining ROP diagnosis speed using indirect ophthalmoscopy versus telemedicine, remote medical consultation, is featured in the July issue of the American Journal of Ophthalmology, published by Elsevier.
The influenza virus that wreaked worldwide havoc in 1918-1919 founded a viral dynasty that persists to this day, according to scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. In an article published online on June 29 by the New England Journal of Medicine, authors Anthony S. Fauci, M.D., Jeffery K. Taubenberger, M.D., Ph.D., and David M. Morens, M.D., argue that we have lived in an influenza pandemic era since 1918, and they describe how the novel 2009 H1N1 virus now circling the globe is yet another manifestation of this enduring viral family.
Visitors can see how their stress levels could affect the heart rate of their unborn baby and find out why pregnant women should reduce their anxiety, at a new exhibit at the Royal Society Summer Science Exhibition, which opens today (30 June 2009).
A new scientific system developed by a St. Michael"s Hospital physician, designed to rapidly evaluate the world"s air traffic patterns, accurately predicted how the H1N1 virus would spread around the world, according to research published in the New England Journal of Medicine.
Commenting on the publication of the results of a national patient access survey today (Tuesday, 30 June 2009) local general practitioners expressed anger that a survey which shows how well general practice is delivering care to patients has resulted in the expected loss of up to ÷£2 million of funding for local GP services. For example, one practice in Northern Ireland with a list size of over 9,000 has lost all of its funding for patient access. Despite providing both 48 hour access and offering the option for patients to book ahead, the perception of just 3% of its patients has resulted in a loss of approximately ÷£15,000 in funding for services.
New data from an economic analysis presented today at this year"s European Society of Human Reproduction and Embryology (ESHRE) congress showed that, within the parameters of the simulation model used, the in vitro fertilisation (IVF) treatment MENOPUR (highly-purified human menopausal gonatropin or HP-hMG) offered considerable cost-savings over recombinant follicle stimulating hormone (rFSH).1 The cost-effectiveness of HP-hMG compared with rFSH suggested by this data could make it a more attractive choice for use in infertility treatment within a fixed healthcare budget.
Doctors at the Cedars-Sinai Heart Institute announced today the completion of the first procedure in which a patient"s own heart tissue was used to grow specialized heart stem cells that were then injected back into the patient"s heart in an effort to repair and re-grow healthy muscle in a heart that had been injured by a heart attack.
Tuberculosis (TB) experts at Johns Hopkins have evidence from a four-year series of experiments in mice that anti-inflammatory drugs could eventually prove effective in treating the highly contagious lung disease, adding to current antibiotic therapies.
BioSante Pharmaceuticals, Inc. (NASDAQ: BPAX), which is developing a testosterone gel (LibiGel®) to treat hypoactive sexual desire disorder (HSDD) in women, is pleased to comment on results in a paper published in the July issue of The Journal of Sexual Medicine showing testosterone has no effect on the incidence of invasive breast cancer among menopausal women who use testosterone to improve sexual function.
"Four divisive issues could dash President Barack Obama"s hopes of overhauling health care: cost, creating a government-run plan, taxing workers" benefits and penalizing employers that don"t offer coverage," the Associated Press/Boston Globe reports.
"Lawmakers working to overhaul the U.S. health-care system face a pressure-filled July after leaving town this week without resolving the biggest questions dividing Democrats and Republicans," Bloomberg reports. Democrats on the Senate Finance Committee - which observers deem most likely to come up with a passable, bipartisan bill - have been working to reduce the cost of the overhaul to gain Republican support, but had not yet released a proposal. Bloomberg adds: "While the Congressional Budget Office said options under consideration by the committee can keep the cost within Baucus"s goal of $1 trillion over 10 years, how to pay for the plan remains unsettled. So is structuring some kind of government-run competition for insurers. ... "Nothing has been set," Montana Democrat [Max] Baucus told reporters in the Capitol on June 25. The recess offers a chance for "taking stock," he said" (Jensen and Livkin, 6/29).
Senate Democrats and Obama administration officials hoping that preventive care would create federal savings have been disappointed to learn that it does not create expected cost savings.
A spokesperson from the vaccine manufacturer Roche confirmed reports Monday that a Denmark patient with H1N1 (swine flu) developed resistance to the antiviral Tamiflu, a drug known to decrease the spread and severity of the virus, Reuters reports (Cage/Arnold, 6/29). According to the AP/News & Observer, the patient has since recovered.
A minimally invasive procedure to treat tendonitis in the rotator cuff of the shoulder provides immediate symptom relief to the patient, according to a study published in the July issue of Radiology. The study found that ultrasound-guided nonsurgical therapy significantly reduces pain from calcific tendonitis of the rotator cuff and restores lasting mobility after treatment.
Siemens Hearing Instruments has kicked off its new education initiative during Deaf Awareness Week with a visit by its hearing ambassador Kellie Moody to a Birmingham based deaf school. The visit and the launch of an education focused website ties into this year"s Deaf Awareness theme of "look at me".
Researchers have found evidence that chronic disease in either a mother or father can create unfavourable conditions in the womb that are associated with the development of polycystic ovarian syndrome (PCOS) in daughters. In another study, researchers found that brothers of women with PCOS and insulin resistance are themselves at greater risk of developing insulin resistance or diabetes, suggesting that factors associated with the condition can be passed down to sons as well as daughters.
Wide gaps in quality outcomes for women persist, not only when compared to men, but among hospitals and states, according to a new study released by HealthGrades, the leading independent healthcare ratings organization. The Sixth Annual HealthGrades Women"s Health in American Hospitals study identifies patient outcomes for maternity care and inhospital treatment of 16 procedures/diagnoses concerning women"s health. Ratings for individual hospitals have been posted at www.healthgrades.com.
Though many consider teaching math to young children to be unnecessary or inappropriate at this stage in their educational development, research shows that as early as infancy, children start to think about the world in mathematical ways -- a capacity that currently goes largely untapped in the nation"s preschools. In addition, studies have linked early success in math to later success in both math and reading.
The misleading "health" halo surrounding highly-publicized marketing campaigns regarding sweetener reformulations is starting to dim.
A team of Harvard scientists has taken an important first step toward the development of new treatments to help people with HIV battle Mycobacterium tuberculosis (TB) infection. In their report, appearing in the July 2009 print issue of the Journal of Leukocyte Biology they describe how HIV interferes with the cellular and molecular mechanisms used by the lungs to fight TB infection. This information is crucial for researchers developing treatments to help people with HIV prevent or recover from TB infection.
Researchers at the University of Michigan have devised a microscale tool to help them understand the mechanical behavior of biofilms, slimy colonies of bacteria involved in most human infectious diseases.
The search is on for fifty cancer patients undergoing chemo or radiotherapy to trial an innovative, natural cosmetic product, Evonail, aimed at reversing the damage done to cracked or broken nails during anti-cancer treatments.
Pfizer Inc announced the discontinuation of the SUN 1122 Phase 3 trial that evaluated Sutent® (sunitinib malate) plus FOLFIRI (irinotecan plus infusional 5-fluorouracil and leucovorin) versus FOLFIRI alone for the first-line treatment of metastatic colorectal cancer (CRC). The independent Data Monitoring Committee (DMC) found that the addition of sunitinib to the chemotherapy regimen FOLFIRI would be unable to demonstrate a statistically significant improvement in the primary endpoint of progression-free survival (PFS) compared to FOLFIRI alone, in this study. No new safety issues were identified.
Despite rapid advances using a child"s own cord blood stem cells in regenerative therapies to repair damaged tissue due to injury or disease, most pregnant women today don"t learn about the ability to save their newborn"s cord blood. According to research published in the Journal of Reproductive Medicine, 3 out of every 4 pregnant women consider themselves only "minimally informed."
Microbial populations have traditionally been studied in carefully controlled, laboratory-grown cultures. New metagenomic approaches are being developed to study these organisms in environmental or medical samples. The July issue of Cold Spring Harbor Protocols presents a method developed by Holger Daims from the University of Vienna for quantifying populations of microorganisms in a variety of naturally occurring conditions such as plankton samples or biofilms. Use of Fluorescence In Situ Hybridization and the daime Image Analysis Program for the Cultivation-Independent Quantification of Microorganisms in Environmental and Medical Samples combines fluorescent in situ hybridization using rRNA-targeted probes with digital image analysis. The results show an organism"s "biovolume fraction" in a given sample; this indicates the share of biochemical reaction space occupied by the quantified population and can be more relevant ecologically than absolute cell numbers. The article is freely available on the website for Cold Spring Harbor Protocols.
Novocaine? Not necessarily. The widespread belief that dentists rely on Novocaine to make those office visits almost painless needs some updating, according to an article scheduled for the June 29 issue of Chemical & Engineering News, ACS" weekly newsmagazine. In fact, patients are more likely to get any of several other anesthetics than the century-old standby Novocaine, which once reigned as the archetypal dental anesthetic.
Inter Press Service News Agency examines the prevalence of obstetric fistula in the southern region of Senegal. According to state reproductive health officials in the town of Kolda, 58 percent of births take place at home without medical assistance. "Women in the region suffer from exceptionally high rates of fistula," which "occurs when extended pressure damages the soft tissue in a woman"s pelvis during the process of giving birth" and can lead to debilitating complications and ostracization from their families, IPS writes.
Sen. Frank R. Lautenberg (D-NJ) announced 20 New Jersey health centers will receive $16,987,384 to address facility and equipment needs, increase access to health care for underserved populations, and create construction-related jobs. The Capital Improvement Program (CIP) funds are being provided under the Economic Recovery Law signed by President Obama in February.
"In a major break with most other large companies, Wal-Mart Stores Inc. Tuesday told the White House that it supports requiring employers to provide health insurance to workers, a centerpiece of President Barack Obama"s effort to provide near-universal coverage to Americans," The Wall Street Journal reports. "Wal-Mart -- which provides insurance to employees and wants to level the playing field with companies that don"t -- on Tuesday delivered a letter to President Obama taking a different stance." The letter was signed by Wal-Mart Chief Executive Mike Duke, as well as Andrew Stern, president of the Service Employees International Union, and John Podesta, "who led President Obama"s transition team and is chief executive of the Center for American Progress, a liberal-leaning think tank." Wal-Mart"s new stance is "a shift from its previous stance on health-care overhaul and follows years of tussles with organized labor." The Journal adds a caveat: Wal-Mart "isn"t changing its policies. The company says it supports the employer mandate because all businesses should share the burden of fixing the health-care system. ... Wal-Mart"s support for a broad mandate also appears to be aimed at beating back an alternative that may be less favorable to the company. The Senate Finance Committee is considering a measure expected to result in a more burdensome health-insurance requirement for companies that have lower-wage workers" (Adamy and Zimmerman, 7/10).
Community pharmacies are urged to register to participate in Phase 2 of the Dose Administration Aids
Tiffany Niemoller, a 5th year MD/PhD student at LSU Health Sciences Center New Orleans Schools of Medicine and Graduate Studies, has been awarded a grant in the amount of $148,480 over four years by the National Institute on Aging of the National Institutes of Health. A training grant for individual predoctoral students, the Ruth L. Kirschstein National Research Service Award is an individual fellowship (F30) is given to "promising applicants with the potential to become productive, independent, highly trained physician-scientists." It is a very competitive grant. The project is being supported with funds from the American Recovery and Reinvestment Act.
Janet Davison Rowley, MD, a founder in the field of cancer cytogenetics and a renowned leader in molecular oncology, will receive the 2009 Genetics Prize of The Peter and Patricia Gruber Foundation. She is being honored with the prestigious international award for discoveries of recurrent chromosomal abnormalities in leukemias and lymphomas - discoveries that have revolutionized how cancer is understood and treated. Currently the Blum-Riese Distinguished Service Professor at the University of Chicago, Rowley is also being honored for her critical national and international leadership in the biomedical research community. The Prize will be presented in Honolulu, Hawaii, on October 23 at the 59th Annual Meeting of the American Society of Human Genetics.
The state Division of Senior and Disabilities Services is working this summer in coordination with the Centers for Medicare & Medicaid Services (CMS) to improve its compliance with federal standards in the areas of Home and Community Based Medicaid Waivers and Personal Care Services (Personal Care Assistance).
Liver transplantation offers a good chance for survival for patients with drug induced acute liver failure, however, certain pre-transplant factors are associated with worse outcomes. Patients who are on life support, who have elevated serum creatinine, and children whose liver failure was caused by antiepileptic drugs did not fare as well after transplantation. These findings are in the July issue of Liver Transplantation, a journal published by John Wiley & Sons. The article is also available online at Wiley Interscience.
GP phone consultations carry definite risks, warns an article in the current edition of Medical and Dental Defence Union of Scotland (MDDUS) magazine Summons today (Thursday, 2 July).
Counseling patients with non-alcoholic fatty liver disease (NAFLD) on how to increase physical activity leads to health benefits that are independent of changes in weight. These findings are in a new study in the July issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience.
Doctors attending the BMA"s annual conference in Liverpool have today (Thursday 2 July 2009) backed calls to introduce a minimum price for a unit of alcohol. Proposing a motion which also included calls for clearer labelling and a total ban on alcohol advertising, Dr Chandra Mohan from Barking, Havering and Brentwood, said:
HIV-infected infants risk contracting a deadly form of tuberculosis from the bacille Calmette-Guerin (BCG) vaccine, instead of receiving protection against the disease, according to research published today in the international public health journal, the Bulletin of the World Health Organization.
Cancer experts at Johns Hopkins say a study tracking 774 prostate cancer patients for a median of eight years has shown that a three-way combination of measurements has the best chance yet of predicting disease metastasis.
Treatment with proton pump inhibitors (PPIs) for eight weeks induces acid-related symptoms like heartburn, acid regurgitation and dyspepsia once treatment is withdrawn in healthy individuals, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.
A Decade-Long campaign by the British Psychological Society to have statutory regulation for practitioner psychologists comes to fruition.
Acura Pharmaceuticals, Inc. (Nasdaq: ACUR) and King Pharmaceuticals, Inc. (NYSE: KG) announced today that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter regarding the New Drug Application (NDA) for Acurox (oxycodone HC1, USP and niacin, USP) Tablets CII, an immediate release product intended for the relief of moderate-to-severe pain.
PTSD (Post-Traumatic Stress Disorder) is triggered by a traumatic event - it is a kind of anxiety. The sufferer of PTSD may have experienced or seen an event that caused extreme fear, shock and/or a feeling of helplessness. Most of us experience a brief period of difficulty adjusting and coping with traumatic events. However, we gradually get better with time and healthy coping methods. On the other hand, there are times when symptoms get worse and may last for several months, or years. This study explains how PTSD can surface two years after a traumatic event. Another study found that one in eight Lower Manhattan residents likely had PTSD two to three years after the 9/11 attacks.
This statement updates Members on the Influenza A (H1N1) swine flu outbreak and the latest developments in Wales, across the UK and internationally.
-- 34 confirmed cases in Wales, with 4 new cases:
As President Barack Obama calls for streamlining heath care by fully converting to electronic medical records and as Congress prepares to debate issues of patient privacy, one question has largely gone unasked: What do patients want?
Politico"s Blog "Under the Radar" explores the HHS" recent decision to revise documents submitted to the Federal Register regarding a change in HIV-related immigration policy.
Patients will continue to be unprotected if statutory independent regulation is not extended to counsellors and psychotherapists, according to leading national charities Mind and WITNESS. On the day that psychologists are to be regulated by the Health Professions Council (HPC), the charities welcome the advancement and urge counsellors and psychotherapists to follow suit.
The American Pharmacists Association (APhA) submitted comments to the Office of the National Coordinator for Health Information Technology"s (ONC) request for feedback on determining criteria for the term "meaningful use" of electronic records (EHRs), prepared by ONC"s HIT Policy Committee.
New research shows that 70 per cent of adults in the UK back proposals to protect children from tobacco by putting it out of sight in shops and 76 per cent support abolishing cigarette vending machines according to Cancer Research UK today (Wednesday) - on the second anniversary of the smoking ban in England.
Skin from a factory - this has long been the dream of pharmacologists, chemists and doctors. Research has an urgent need for large quantities of "skin models", which can be used to determine if products such as creams and soaps, cleaning agents, medicines and adhesive bandages are compatible with skin, or if they instead will lead to irritation or allergic reactions for the consumer. Such test results are seen as more meaningful than those from animal experiments, and can even make such experiments largely superfluous.
Statement of Captain Charles D. Connor, U.S. Navy (Ret.), American Lung Association President and CEO: